Liquid Chromatograph, HPLC-W3400

Features

1. Rapid Separation Liquid Chromatography(RSLC) System

• Separable Modular Structure: Multiple RSLC main unit models available for customizable configurations.
• Comprehensive Detector Range: Includes UV, DAD, FLD, ELSD, and RID detectors with intelligent control.
• Smart Lab Workstation: Simplifies complex tasks with user-friendly interfaces.
• Chromatography Consumables: Can be selected as needed.

2. Needle-in-FlowInjection System

• Flow to Needle Injection System: Eliminates sample loss and minimizes cross-contamination.
• Advanced Online Functions: Supports online derivatization, dilution, and enrichment.
• Optimized Needle Cleaning: This design reduces contamination risk.
• Global Standard Performance: Ensures better qualitative and quantitative reproducibility.

3. Extended Functions to Meet Diverse User Needs

• Enhanced Compatibility: Innovative one-way valve technology ensures acetonitrile compatibility.
• Column oven with valve switching, providing 2 installation clips for 250mm HPLC columns, expandable to 4+ columns.
• Innovative Technology: Effectively identifies shoulders and small peaks with guided operation and intelligent integration.

Key Components

High-Pressure Pump Maximum Pressure and Compatibility: Capable of withstanding up to 75MPa, compatible with smaller particle size chromatographic columns, enabling seamless method transfer. Acetonitrile-Resistant Valve: Features a high-precision, self-restoring, acetonitrile-resistant one-way check valve, ensuring stable fluid delivery in acetonitrile applications. The further optimized two-stage floating technology significantly reduces wear on highpressure seals, extending the lifespan of consumables. Flow Stability and Gradient Accuracy: Proprietary fluid compression compensation technology with real-time feedback electronic pulsation suppression control ensures stable flow and precise gradient accuracy. Quaternary Pump with Degassing: Quaternary pump integrated with 5-channel degassing (A, B, C, D, AS). Binary Pump with Solvent Switching: The binary pump comes with a standard solvent switching valve, enabling binary and four-way expansion for analysis. User-Friendly Design: Equipped with a touch panel switch, meeting the needs for offline operation and human-machine separation.
Auto sampler  Needle-in-flow design ensures zero sample loss during injection. Compatible with different specifications of sample trays, expanding user application scenarios. Metering pump for precise sampling, offering longer lifespan and higher accuracy compared to syringe pumps. Optimized needle cleaning flow path minimizes cross-contamination, ensuring sample purity. Standard obstacle protection function effectively prevents damage to the injection needle. Standard empty bottle detection function to prevent invalid sample injection. Full range of sample pretreatment functions supporting online enrichment, online derivatization, online dilution and mixing, further expanding user method development scenarios. Optional refrigeration component to ensure detection accuracy of thermally unstable substances. Optional condensation peristaltic pump active drainage function to effectively prevent damage to the equipment from overflow of condensation accumulation. Pump and autosampler can be linked for purge operation, eliminating the need for manual purge valve operation.
Column Oven Default configuration with semiconductor cooling module and electric-resistive heating module, achieving full temperature range control with heating and cooling functions. Two control modes ensure longer lifespan and higher reliability of temperature control components. Forced air circulation for precise and uniform temperature control throughout the chamber. Standard preheating module with the same temperature range as the set temperature to ensure optimal temperature consistency. Multi-column capacity design supporting up to 3 chromatographic columns of 300mm. Supports upgrade to 2D configuration with built-in high-pressure switching valve, and can be expanded to support multiple external switching valve. Optional chromatographic column GLP information recording function

Full Range of Liquid Chromatography Detectors

	Diode Array Detector Capable of acquiring chromatographic signals across all wavelengths from 190 to 800nm, exhibiting detailed spectral structures. Features a high-intensity deuterium lamp, concave holographicgrating, 1024-element photodiode array, and all-solid-state, highly stable optical path structure. Provides three-dimensional spectra, contour plots, chromatograms, spectra, maximum intensity plots, and other information to supportmultiple application needs, including advanced functions such as peak purity calculations. Achieves extreme low signal noise and drift through independent chamber temperature control, active fan speed control, and passive temperature stabilization of internal materials.
	Refractive Index Detector Designed with a two-chamber configuration and upgraded to a long-life LED light source for maintenance-free operation over its lifetime. Freely switchable between entryand exit of rinse modes for automatic rinsing of the reference flow Utilizesa high-precision data acquisition system with sequential rinsing, polarity control, and temperature control. Imported PD tube ensures high sensitivity. Equipped with temperature and leak detection alarms for real-time monitoring of instrument status. Features a touch-sensitive LCD display supporting both local user control and chromatography software workstation modes. Supports analog and digital signal outputs, compatible with chromatography systems from other brands.
	Ultraviolet Detector Dual-lamp design with a high-transparency deuterium lamp and an optional tungsten lamp, greatly extending the detector’s detection range and enabling full-range detection from 188nm to 900nm. Built-in multi-dimensional wavelength calibration functions (including holmium oxide, potassium dichromate, erbium perchlorate, and deuterium lamp characteristic wavelength calibration) for extremely high wavelength accuracy. Capabilities include flow-stop spectra scanning, dual-wavelength detection, and wavelength programming. Supports proportional chromatogram analysis and aids in extended peak purity analysis.
	Fluorescence Detector Dual monochromator structure allows flexible setting of excitation and emission wavelengths,simultaneously monitoring four wavelength channels. Supportsmultiple scanning modes including laser spectral scanning, emission spectral scanning, and lamp spectrum scanning. Provides a stable light source with a direct-current xenon lamp, and multi-level precision detection gain settings for a large dynamic range and high signal-to-noise ratio. Features a touch-sensitive LCD display supporting both local user control and chromatography software workstation modes. Supports analog and digital signal outputs, compatible with chromatography systems from other brands.
	Evaporative Light Scattering Detector Designed for low-temperature evaporation, offering high sensitivity for thermally unstable and semi-volatile compounds. Built-in gas mass flow meter with capillaryheat transfer differential calorimetry for precise gas flow control. Independent flow control for nebulization, evaporation, and detection ensures excellent response reproducibility. Drift tube features corrosion-resistant treatment and stainless steel construction (excluding fragile glass and easily corroded components). Imported nebulizer and photomultiplier tube ensure high signal sensitivity, long lifespan, and wide adjustable range. Equipped with temperature, leak, and gas leakage detection alarms for real-time monitoring of instrument status. Features a touch-sensitive LCD display supporting both local user control and chromatography software workstation modes. Supports analog and digital signal outputs, compatible with chromatography systems from other brands.

Smart Lab Chromatography Workstation

1. Validated at CMMI Maturity Level 5, which ensures international quality standards for software development.
2. Featuring a comprehensive audit trail function compliant with GMP, CGMP, 21 CFRPart 11, ICH guidelines, and other laws and regulations, ensuring full-process data traceability. Audit trail records are not allowed to be edited and deleted and can be printed.
3. Convenient data organization and storage capabilities, utilizing an efficient database system to safeguard user data Automatic backups and cyclic updates ensure complete backups within the latest 7 days, preventing data loss.
4. Features the SmartPeak intelligent peak detection function, and employing a second-order algorithm combined withGaussian, exponential, and tangent skimming to achieve effective identification and intelligent selection of chromatographic peaks screenshots of shoulder peak recognition and advanced skimming software provided). This simplifies the integration process, providing consistent and reliable peak detection across multiple chromatograms.
5. Modularized device components enable integration with third-party manufacturers. Full control capabilities for multi-brand and multi-model instruments provide ample scalability for future laboratories.